This is the only Edwin painting I've seen of man-made objects. Click the image for a 650KB file, suitable for printing, Owned by the Minneapolis Institute of Arts.
When Edwin painted this scene, he was running his father's baking powder factory. He left that and spent the next 30 years on natural scenes. Edwin once said
“there is a quality in nature which no painter seems to have expressed. That is the ‘something’ which I seek to present. I may never succeed in depicting it, but I am going to have a serious try at it. It is a joy to strive for it, even though one may never interpret it. It seems to me the trouble lies chiefly in the fact that the closer one comes to expressing an ideal, the further one sees beyond.”
Here's a catalog entry from a book on Minnesota art describing Channel to the Mills:
Edward M Dawes began his career as a self-taught sign painter, and gained fame as a Minnesota landscapist and later painted in Nevada and California. Channel to the Mills treats Minnesota’s most frequently painted cityscape, the flour mills that line the banks of the Mississippi River in Minneapolis and which produced the city’s wealth for decades. Dawes’ major work in Minnesota, the painting plays the curves of water and smoke against the geometric battlements of the massive stone mills.
Edwin's foreground shows a wasteland, with a grimy-looking channel carved by nature coming from the mills. While industrialists of the era saw wealth in the mills, Edwin also painted the damage that industry causes. In my 40 years as a plant chemist, I was pleased that government finally started taking serious actions to control pollution.